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´ú±íÂÛÎÄ:

Zhang Y, Chen Q. Changes of matrilin forms during endochondral ossification: molecular basis of oligomeric assembly. J Biol Chem, 275(42):32628-32634, 2000. PMID: 10930403

Wu Q, Chen Q. Mechanoregulation of chondrocyte proliferation, maturation, and hypertrophy: ion-channel dependent transduction of matrix deformation signals. Exp Cell Res, 256, 383-391, 2000. PMID: 10772811

You J, Reilly G, Zhen X, Yellowley CE, Chen Q, Donahue HJ, Jacobs CR. Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts. J Biol Chem, 276(16): 13365-13371, 2001. PMID: 11278573

Wu Q, Zhang Y, Chen Q. Indian hedgehog is an essential component of mechanotransduction complex to stimulate chondrocyte proliferation. J Biol Chem, 276(38): 35290-35296, 2001. PMID: 11466306

Zhen X, Wei L, Wu Q, Zhang Y, Chen Q. Mitogen-activated protein kinase p38 mediates regulation of chondrocyte differentiation by parathroid hormone. J Biol Chem, 276(7): 4879-4885, 2001. PMID: 11098049

Kanbe K, Takagishi K, Chen Q. Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell-derived factor 1 and CXC chemokine receptor 4 (Reply to study of SDF-1 alpha synovial fluid in early rheumatoid arthritis). Arthritis Rheum, 48:275-276, 2003. PMID: 11817585

Phornphutkul C, Wu KY, Yang X, Chen Q, Gruppuso PA. Insulin-like Growth Factor-I signaling is modified during chondrocyte differentiation. J Endocrinology, 183: 477-486, 2004. PMID: 15590974

van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q. Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol 169:515-27, 2006. PMID: 16877353 / PMCID: PMC1698783

Wei L, Sun X, Wang Z, Chen Q. CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase. Arthritis Res Ther 8(2):R37, 2006. PMID: 16469115 / PMCID: PMC1526592

Wei L, Sun X, Kanbe K, Wang Z, Sun C, Terek R, Chen Q. Chondrocyte death induced by pathological concentration of chemokine stromal cell-derived factor-1. J Rheumatol 33:1818-26, 2006. PMID: 16960943

Lee M, Bier A, Nickish F, Eberson C, Ehrlich MG, Chen Q. Epiphysiodesis with infusion of stromal cell-derived factor-1 in rabbit growth plates. J Bone Joint Surg Am 89:102-133, 2007. PMID: 17200317

Kanbe K, Yang X, Wei L, Sun, C, Chen Q. Pericellular matrilins regulate activation of chondrocytes by cyclic load-induced matrix deformation, J Bone Miner Res 22:318-328, 2007. PMID: 17129169

Phornphutkul C, Wu K, Auyeung V, Chen Q, Gruppuso P. mTOR signaling contributes to chondrocyte differentiation. Dev Dyn 237(3):702-12, 2008. PMID: 18265001 / PMCID: PMC2768549

Namdari S, Wei L, Moore D, Chen, Q. Reduced limb length and worsened osteoarthritis in adult mice after genetic inhibition of p38 MAP kinase activity in cartilage. Arthritis Rheum 58:3520-29, 2008. PMID: 18975318 / PMCID: 2774253

Pei M, Lou J, Chen Q. Enhancing and maintaining chondrogenesis of synovial fibroblasts by cartilage extracellular matrix protein matrilins. Osteoarthritis Cartilage 16:1110-17, 2008. PMID: 18282772 / PMCID: 2596998

Phornphutkul C, Lee M, Voigt C, Ehrlich MG, Gruppuso P, Chen Q. The effect of rapamycin on bone growth in rabbits, J Orthop Res 27(9):1157-1161, 2009. PMID: 19382193 / PMCID: PMC2894807

Sun XJ, Wei L, Chen Q, Terek RM. HDAC4 represses vascular endothelial growth factor expression in chondrosarcoma by modulating Runx2 activity. J Biol Chem. 284(33): 21881-90, 2009. PMID: 19509597 / PMCID: PMC2755912

Sun X, Wei L, Chen Q, Terek RM. CXCR4/SDF1 mediate hypoxia induced chondrosarcoma cell invasion through ERK signaling and increased MMP1 expression. Mol Cancer 9:17, 2010. PMID: 20102637 / PMCID: PMC2825244

Wei L, Fleming BF, Sun XJ, Teeple E, Wu W, Jay GD, Elsaid KA, Luo J, Machan JT, Chen Q. Comparison of differential biomarkers of osteoarthritis with and without posttraumatic injury in the Hartley guinea pig model. J Orthop Res 28:900-6, 2010. PMID: 20108346 / PMCID: PMC2875364

Wei L, Kanbe K, Lee M, Wei X, Pei M, Sun X, Terek R, Chen Q. Stimulation of chondrocyte hypertrophy by chemokine stromal cell-derived factor 1 in the chondro-osseous junction during endochondral bone formation. Dev Biol 341:236-45, 2010. PMID: 20206617 / PMCID: PMC2862458

Guan YJ, Yang X, Wei L, Chen Q. MiR-365: A mechano-sensitive microRNA stimulates chondrocyte differentiation through targeting Histone Deacetylase 4. FASEB J, 25(12):4457-66. Epub 2011 Aug 19, 2011, PMID:21856783/PMCID: PMC3236620

Guan Y, Chen Q, Yang X, Haines P, Pei M, Terek R, Wei X, Zhao T, Wei L. Subcellular Relocation of Histone Deacetylase 4 Regulates Growth Plate Chondrocyte Differentiation through Ca2+/Calmodulin-Dependent Kinase IV. American Journal of Physiology-Cell Physiology, 2012; 303(1):C33-40. PMID: 22442139

Zhao J, Xia W, Nie M, Zheng X, Wang Q, Wang X, Wang W, Ning Z, Huang W, Jiang Y, Li M, Wang O, Xing X, Sun Y, Luo L, He S, Yu W, Lin Q, Pei Y, Zhang F, Han Y, Tong Y, Che Y, Shen R, Hu Y, Zhou X, Chen Q, Xu L. A haplotype of MATN3 is associated with vertebral fracture in Chinese postmenopausal women: Peking Vertebral Fracture (PK-VF) study. Bone. 2012 Apr;50(4):917-24. Epub 2012 Jan 16. PMID 22270056

Wei F, Zhou J, Wei X, Zhang J, Fleming BF, Terek R, Pei M, Chen Q, Liu T, Wei L. Activation of Indian Hedgehog Promotes Chondrocyte Hypertrophy and Upregulation of MMP-13 in Human Osteoarthritic Cartilage, Osteoarthritis & Cartilage, 2012;20(7):755-63. PMID: 224698532012

Li J, Huang J, Dai L, Yu D, Chen Q, Zhang X, Dai K. MiR-146a, an IL-1beta Responsive MicroRNA, Induces VEGF and Chondrocyte Apoptosis by Targeting Smad4, Arthritis Research & Therapy, 2012 14(2):R75. PMID:22507670

Desai HV, Voruganti IS, Jayasuriya C, Chen Q, Darling EM. Live-cell, temporal gene expression analysis of osteogenic differentiation in adipose-derived stem cells, 2012, Tissue Engineering Part A, 2012, Jul 28. [Epub ahead of print]. PMID:22840182

Weng T, Yi L, Huang J, Luo F, Wen X, Du X, Chen Q, Deng C, Chen D, Chen L. Genetic inhibition of FGFR1 in cartilage attenuates articular cartilage degeneration in adult mice. Arthritis Rheum. 2012 Jul 25. doi: 10.1002/art.34645. [Epub ahead of print] PMID: 22833219

Jayasuriya CT, Goldring MB, Terek RM, Chen Q. Matrilin-3 induction of IL-1 receptor antagonist is required for up-regulating collagen II and aggrecan as well as down-regulating ADAMTS-5 gene expression, Arthritis Research & Therapy, 2012, Sep 11;14(5):R197. PMID: 22967398

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