öλÔÓéÀֵǼÈë¿ÚÏÂÔØ

×ÚÀò£¬Ò©¼ÁѧöλÔÓéÀֵǼÈë¿ÚÏÂÔؽÌÊÚ£¬²©Ê¿Éúµ¼Ê¦£¬Ò©Ñ§²©Ê¿¡£öλÔÓéÀֵǼÈë¿ÚÏÂÔØÑо¿·½Ïò£º»º¿ØÊÍÖƼÁºÍÉúÎï¼¼ÊõÒ©ÎïµÝËÍϵͳ¡£ÔÚ»º¿ØÊÍÖƼÁÁìÓò£¬ÓжþÊ®¶àÄêÑо¿¾­Àú£¬Ñо¿ÐËȤ£ºÔñʱ¿ØÊÍÖƼÁ¡¢ÄÑÈÜÒ©ÎﻺÊÍÖƼÁ¡£×Ô2002ÄêÉæ×ãÉúÎï¼¼ÊõÒ©ÎïµÝËÍϵͳ£¬»ñ´ËÁìÓò2004Äê¡¢2006ÄêºÍ2010Äê¶È¹ú¼Ò×ÔÈ»¿Æѧ»ù½ð£¬Ñо¿ÐËȤ£º»ùÒòµÝҩϵͳ¡¢Õ³Ä¤ÃâÒß¡¢¶àëÄ/µ°°×ÖÊ·Ç×¢Éä¸øÒ©¡£

¿ÆÑгɹû£ºÖ÷³ÖÍê³É¹ú¼Ò×ÔÈ»¿Æѧ»ù½ðÏîÄ¿3Ïî¡¢ÄþÏÄ¿Æί¹¥¹ØÏîÄ¿1ÏîºÍ½­ËÕÊ¡¸ßм¼Êõ´´ÒµÖÐÐÄÏîÄ¿1Ïî¡£²ÎÓëÍê³ÉʮһÎå¹ú¼Ò“ÖØ´óÐÂÒ©´´ÖÆ”¿Æ¼¼ÖØ´óרÏî¡¢“863”ÏîÄ¿¡¢“°ËÎ唹ú¼ÒÖصã¿Æ¼¼¹¥¹ØÏîÄ¿ºÍ½­ËÕÊ¡×ÔÈ»¿Æѧ»ù½ðÏîÄ¿¡£

½üÄêÒÔÏîÄ¿¸ºÔðÈË»ñÐÂÒ©Ö¤Êé3±¾¡¢Ò»ÀàÐÂÒ©ÁÙ´²ÅúÎÄ1·Ý¡£Ð­ÖúÆóÒµÍê³É¶àÏîÐÂÒ©µÄ²úÒµ»¯×ª»¯£¬»ñÒ©Æ·×¢²áÅú¼þ4·Ý¡£ÁíÍâÒÔ·Ö¿ÎÌ⸺ÔðÈ˲ÎÓëÍê³ÉÐÂÒ©²úÆ·3Ïî¡£ÒÔµÚÒ»·¢Ã÷ÈË»ñÐÂÖƼÁºÍй¤ÒÕÊÚȨרÀû6ÏÆäÖÐ3ÏîרÀûȨתÈûòרÀûʵʩÐí¿É¡£

³Ðµ£±¾¿ÆÉú¿Î³Ì¡¶Ò©¼Áѧ¡·¡¢Ë¶Ê¿Éú¿Î³Ì¡¶ÉúÎïÒ©¼Áѧ¡·ºÍ¡¶ÏÖ´úÒ©¼ÁѧѡÂÛ¡·½Ìѧ¹¤×÷£¬ÔÚ¹ú¼ÊºÍ¹úÄÚºËÐÄÆÚ¿¯·¢±íÑо¿ÂÛÎÄ40Óàƪ£¬»ñ2008ºÍ2009Äê¶È½­ËÕÊ¡ÓÅÐã˶ʿѧλÂÛÎÄ2ƪ£¬»ñ2011Äê½­ËÕÊ¡Ñо¿Éú¿ÆÑд´Ð¼ƻ®ÏîÄ¿µÈ¡£

½ü5Äê·¢±íµÄÖ÷ÒªÎÄÕ£º

[1]Xiying Yuan, Xiaorong Yang, Danning Cai, Dan Mao, Jie Wu, Li Zong* et al. Intranasal immunization with chitosan/pCETP nanoparticles inhibits atherosclerosis in a rabbit model of atherosclerosis. Vaccine 2008, 26: 3727-3734

[2]Xiaorong Yang, Xiying Yuan, Danning Cai, Shaoying Wang, Li Zong* Low molecular weight chitosan in DNA vaccine delivery via mucosa. Int J Pharm, 2009, 375: 123-132

[3]Fang J, Lu Y, Ouyang K, Wu G, Zhang H, Liu Y, Chen Y, Lin M, Wang H, Jin L, Cao R, Roque RS, Zong L, Liu J, Li T. Specific antibodies elicited by a novel DNA vaccine targeting gastrin-releasing peptide inhibit murine melanoma growth in vivo.Clin Vaccine Immunol, 2009, 16: 1033-1039

[4]Hou Jing, Lu Yong, Liu Haiyan, Zong Li*, Liu Jingjing, Oral administration of Lactococcus lactis delivered heat shock protein 65 attenuates atherosclerosis in low-density lipoprotein receptor-deficient mice. Vaccine 2011, 29: 4102-4109

[5]Wenjun Yao, Yan Jiao, Juan Luo, Mingzhu Du, Li Zong*, Practical synthesis and characterization of mannose-modified chitosan. Int J Biol Macromol, 2012, 50: 821-825

[6]Ling Wang, Fan Zeng, Li Zong*, Development of orally disintegrating tablets of Perphenazine/hydroxypropyl-β-cyclodextrin inclusion complex. Pharm Dev Technol, 2013, 18: 1101-1110

[7]Zeng F, Wang L, Zhang W, Shi K, Zong L*. Formulation and In Vivo Evaluation of Orally Disintegrating Tablets of Clozapine/Hydroxypropyl-β-cyclodextrin Inclusion Complexes. AAPS PharmSciTech, 2013, 14: 854-860

[8]Yao Wenjun, Peng Yixing, Du Mingzhu, Luo Juan, Zong Li*. Preventative vaccine loaded mannosylated chitosan nanoparticles intended for nasal mucosal delivery enhance immune responses and potent tumor immunity. Mol Pharm, 2013, 10: 2904-2914

[9]Su Z, Shi Y, Xiao Y, Sun M, Ping Q*, Zong L*, et al. Effect of octreotide surface density on receptor-mediated endocytosis in vitro and anticancer efficacy of modified nanocarrier in vivo after optimization. Int J Pharm, 2013, 447: 281-192

[10]Ling Wang, Yanyu Xiao, Minglei Chen, Fan Zeng, Li Zong*, Pharmacokinetics of orally disintegrating tablets of perphenazine/hydroxypropyl-β-cyclodextrin inclusion complex in rabbits. Pharmazie, 2013, 68: 1-5

ÁªÏµ·½Ê½£ºTel:025£­83271317£»13951603932

E-mail:zongcpu@hotmail.com