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[1]A. Schulz, S. Jaksch, R. Schubel, E. Wegener, Z.Y. Di, Y.C. Han, A. Meister, J. Kressler, A.V. Kabanov, R. Luxenhofer, C.M. Papadakis, R. Jordan. Drug-Induced Morphology Switch in Drug Delivery Systems Based on Poly(2-oxazoline)s . ACS NANO, 2014, 8(3): 2686-2696.
[2]Y.C. Han, X.Y. Wang, H.L. Dai, S.P. Li. Synthesis and luminescence of Eu3+ doped hydroxyapatite nanocrystallines: Effects of calcinations and Eu3+ content. Journal of Luminescence, 2013, 135:281-287
[3]Y.C. Han, X.Y. Wang, H.L. Dai, S.P. Li. Nanosize and Surface Charge Effects of Hydroxyapatite Nanoparticles on Red Blood Cell Suspensions. ACS Appl. Mater. Interfaces, 2012, 4 (9):4616–4622.
[4]Y.C. Han, Z.J. He, A. Schulz, T.K. Bronich, R. Jordan, R. Luxenhofer, A.V. Kabanov. Synergistic Combinations of Multiple Chemotherapeutic Agents in High Capacity Poly(2-oxazoline) Micelles. Mol. Pharmaceutics, 2012, 9 (8): 2302–2313.
[5]R. Luxenhofer, Y.C. Han, A. Schulz, J. Tong, Z.J. He, A.V. Kabanov, R. Jordan. Poly(2-oxazoline)s as polymer therapeutics. Macromol Rapid Commun. 2012, 33(19):1613-1631.
[6]Y.C. Han, X.Y. Wang, S.P. Li. Biocompatible Europium doped Hydroxyapatite Nanoparticles as a Biological Fluorescent Probe. Current Nanoscience, 2010, 6(2): 178-183.
[7]Y.C. Han, X.Y. Wang, S.P. Li. A simple route to prepare stable hydroxyapatite nanoparticles suspension. Journal of Nanoparticle Research, 2009, 11(5): 1235-1240.
[8]I. Bauer, S.P. Li, Y.C. Han, L. Yuan, M.Z. Yin. Internalization of hydroxyapatite nanoparticles in liver cancer cells. Journal of Materials Science: Materials in Medicine, 2008, 19(3): 1091-1095.
[9]ÃÀ¹ú·¢Ã÷רÀû: US7989532 B2. RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material and preparation method thereof. Li Shipu, Han Yingchao, Yan Yuhua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao. 2011.8ÊÚȨ
[10]Å·ÖÞ·¢Ã÷רÀû: EP2039377 B1. RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material and preparation method thereof. Li Shipu, Han Yingchao, Yan Yuhua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao. 2012. 9ÊÚȨ
ÁªÏµ·½Ê½:
µç»°:18986218516, 15927360395
E-mail:hanyingchao@whut.edu.cn
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Name: Yingchao Han
Personal information
Date of birth: April, 1977
Education: Doctor Degree of Engineering, Wuhan University of Technology
Major: Biomedical materials
Position: Associate Researcher
Work place: Institute of New Materials/Biomedical Materials and Engineering Center
Education
1996.9-2000.7, Bachelor Degree in Materials Science, Wuhan University of Technology, China
2000-2002, Master Degree in Materials Science, Wuhan University of Technology, China
2005-2007, Doctor Degree in Biomedical Materials, Wuhan University of Technology, China
Positions and Employment
2002.7-2004.10 Researcher Assistant, Wuhan University of Technology, P.R. China
2004.11-2009.10 Assistant Researcher, Wuhan University of Technology, P.R. China
2010.6-2012.6 Postdoctoral Research Fellow, University of Nebraska Medical Center
2009.11-present Associate Researcher, Wuhan University of Technology, P.R. China
Research Area and Interests:
1. Bioceramic and biomedical inorganic nanomaterials
1.1 Synthesis of hydroxyapatite (HAP) powders and fabrication of HAP bioceramics;
1.2 Adsorption properties of HAP nanoparticles to some biomolecules (such as serum albumin, heparin and salic acid) and the interaction of HAP nanoparticles cancer cells;
1.3 Preparation and application of rare earth doped HAP nanoparticles with fluorescent property in cell labelling.
1.4 Applications of HAP nanoparticles as drug or gene carriers
2. Drug delivery nano-carrier system and drug formulation
2.1 Preparation technology of anti-cancer drug loading amphiphilic block micelles formulation;
2.2 Synergistic effects study between multiple anti-cancer drugs
Project:
National Natural Science Foundation of China: Preparation and application of rare earth doped hydroxyapatite nanoparticles fluorescence probe
Fundamental Research Funds for the Central Universities: Study on rare earth elements co-doped hydroxyapatite nanoparticles and fluorescence enhancing effect
Opening fund of State Key Laboratory: Controlled preparation of rare earth doped hydroxyapatite nanoparticle and in vivo biodistribution and metabolism
Selected paper and patent (no more than 10)
[1] A. Schulz, S. Jaksch, R. Schubel, E. Wegener, Z.Y. Di, Y.C. Han, A. Meister, J. Kressler, A.V. Kabanov, R. Luxenhofer, C.M. Papadakis, R. Jordan. Drug-Induced Morphology Switch in Drug Delivery Systems Based on Poly(2-oxazoline)s . ACS NANO, 2014, 8(3): 2686-2696.
[2] Y.C. Han, X.Y. Wang, H.L. Dai, S.P. Li. Synthesis and luminescence of Eu3+ doped hydroxyapatite nanocrystallines: Effects of calcinations and Eu3+ content. Journal of Luminescence, 2013, 135:281-287
[3] Y.C. Han, X.Y. Wang, H.L. Dai, S.P. Li. Nanosize and Surface Charge Effects of Hydroxyapatite Nanoparticles on Red Blood Cell Suspensions. ACS Appl. Mater. Interfaces, 2012, 4 (9):4616–4622.
[4] Y.C. Han, Z.J. He, A. Schulz, T.K. Bronich, R. Jordan, R. Luxenhofer, A.V. Kabanov. Synergistic Combinations of Multiple Chemotherapeutic Agents in High Capacity Poly(2-oxazoline) Micelles. Mol. Pharmaceutics, 2012, 9 (8): 2302–2313.
[5] R. Luxenhofer, Y.C. Han, A. Schulz, J. Tong, Z.J. He, A.V. Kabanov, R. Jordan. Poly(2-oxazoline)s as polymer therapeutics. Macromol Rapid Commun. 2012, 33(19):1613-1631.
[6] Y.C. Han, X.Y. Wang, S.P. Li. Biocompatible Europium doped Hydroxyapatite Nanoparticles as a Biological Fluorescent Probe. Current Nanoscience, 2010, 6(2): 178-183.
[7] Y.C. Han, X.Y. Wang, S.P. Li. A simple route to prepare stable hydroxyapatite nanoparticles suspension. Journal of Nanoparticle Research, 2009, 11(5): 1235-1240.
[8] I. Bauer, S.P. Li, Y.C. Han, L. Yuan, M.Z. Yin. Internalization of hydroxyapatite nanoparticles in liver cancer cells. Journal of Materials Science: Materials in Medicine, 2008, 19(3): 1091-1095.
[9] United States Patent: US7989532 B2. RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material and preparation method thereof. Li Shipu, Han Yingchao, Yan Yuhua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao. 2011.8 issued.
[10] European Patent: EP2039377 B1. RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material and preparation method thereof. Li Shipu, Han Yingchao, Yan Yuhua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao. 2012. 9 issued.
Contact information:
Tel:18986218516, 15927360395
E-mail:hanyingchao@whut.edu.cn
Address (Lab): 7th floor, YIFU Building, Wuhan University of Technology