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Ö÷Òª´ú±íÐÔÂÛÎÄ£º1. F. Zhu, Z. Shi, C. Qin, L. Tao, X. Liu, F. Xu, L. Zhang, Y. Song, X.H. Liu, J.X. Zhang, B.C. Han, P. Zhang and Y.Z. Chen. Therapeutic Target Database Update 2012: A Resource for Facilitating Target-Oriented Drug Discovery. Nucleic Acids Res., 40(D1): D1128-D36 (2012).2. F. Zhu, C. Qin, L. Tao, X. Liu, Z. Shi, X.H. Ma, J. Jia, Y. Tan, C. Cui, J.S. Lin, C.Y. Tan, Y.Y. Jiang and Y.Z. Chen. Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting. PNAS., 108(31): 12943-8 (2011).3. F. Zhu, B.C. Han, P. Kumar, X.H. Liu, X.H. Ma, X.N. Wei, L. Huang, Y.F. Guo, L.Y. Han, C.J. Zheng and Y.Z. Chen. Update of TTD: Therapeutic Target Database. Nucleic Acids Res., 38 Suppl 1: D787-91 (2010).4. F. Zhu, L.Y. Han, C.J. Zheng, B. Xie, M.T. Tammi, S.Y. Yang, Y.Q. Wei and Y.Z. Chen. What are next generation innovative therapeutic targets? Clues from genetic, structural, physicochemical and system profile of successful targets. J Pharmacol Exp Ther., 330(1): 304-15 (2009).5. J. Jia, F. Zhu, X.H. Ma, Z.W. Cao, Y.X. Li and Y.Z. Chen. Mechanisms of drug combinations from interaction and network perspectives. Nat. Rev. Drug Discov., 8(2): 111-28 (2009).