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1. Qiujue Xun*, Zhang Zhang*, Jinfeng Luo, Lingjiang Tong, Minghao Huang, zhen Wang, Jian Zou, Yong Xu, Hua Xie, Zheng-Chao Tu, Xiaoyun Lu*, Ke Ding*.Design, Synthesis and Structure-Activity Relationship Study of 2-Oxo-3, 4-dihydropyrimido[4, 5-d] Pyrimidines as New Colony Stimulating Factor-1 Receptor (CSF1R) Kinase Inhibitors. J. Med. Chem. 2018, doi: 10.1021/acs.jmedchem.7b016122. Xiaoyun Lu*, Lei Yu, Zhang Zhang, Xiaomei Ren, Jeff B Smaill, Ke Ding*. Targeting EGFRL858R/T790M and EGFRL858R/T790M/C797S resistance mutations in NSCLC: Current developments in medicinal chemistry. Med. Res. Rev. 2018, doi: 10.1002/med.21488.3. Yu Chang#, Xiaoyun Lu#, Marthiandam Asokan Shibu#, YiBo Dai#, Jinfeng Luo, Yan Zhang, Yingjun Li, Peng Zhao, Zhang Zhang, Yong Xu, Zheng Chao Tu, Qingwen Zhang*, Caihong Yun*, Chih.-Yang Huang*, and Ke Ding*. Structure-Based Design of N-(3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl) Benzenesulfonamides as Selective Leucine- Zipper and Sterile-¦Á Motif Kinase (ZAK) Inhibitors. J. Med. Chem. 2017, 60(13):5927-5932.