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1. Lee H, Abe Y, Lee I, Shrivastav S, Huttemann M, Hopfer U, Felder RA, Jose PA, and Kopp JB. Increased mitochondrial activity in renal proximal tubule cells from young spontaneously hypertensive rats. Kidney Int 2014, 85: 561-569. (IF: 8.563)
2. Li H, Yu P, Sun Y, Felder RA, Periasamy A, and Jose PA. Actin cytoskeleton-dependent Rab GTPase-regulated angiotensin type I receptor lysosomal degradation studied by fluorescence lifetime imaging microscopy. J Biomed Optics 2010, 15: 056003 (1-9). (IF: 3.188)
3. Li H, et al. D1-like receptors regulate NADPH oxidase activity and subunit expression in lipid raft microdomains of renal proximal tubule cells. Hypertension 2009, 53: 1054-1061. (IF: 6.614)
4. Li H, Yu P, Felder RA, Periasamy A, and Jose PA. Angiotensin II-induced angiotensin II type I receptor lysosomal degradation studied by fluorescence lifetime imaging microscopy. SPIE Proc, 2009, 7183: 71832G (1-12).
5. Li H, et al. Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin proteasome pathway in mice and human cells. J Clin Invest 2008, 118: 2180-2189. (IF: 16.559)
6. Li H, Li HF, Felder RA, Periasamy A, and Jose PA. Rab4 and Rab11 coordinately regulate the recycling of angiotensin II type I receptor demonstrated by fluorescence resonance energy microscopy. J Biomed Optics 2008, 13: 031206 (1-10). (IF: 2.97)
7. Li H, et al. Protein kinase A anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide exchange protein 2 (BIG2). Proc Natl Acad Sci USA 2003, 100: 1627-1632. (IF: 10.272)
8. ÀîºÍÍú, ¹¢ÇïÃ÷, ÕÅÓ×âù, º«ÆôµÂ. ¦Á1-ÉöÉÏÏÙËØÊÜÌåÑÇÐͽ鵼ϸ°ûÄÚÓÎÀëCa2+Ôö¸ßµÄÐźÅת µ¼Í¾¾¶£®ÉúÀíѧ±¨ 1998, 50: 349-354.
9. ÀîºÍÍú£¬ÍõÏÜ£¬º«ÆôµÂ. ϸ°ûÄÚÖü´æ¸ÆÊͷŵĻúÖÆ£®ÉúÀí¿Æѧ½øÕ¹ 1995, 26: 209-212.
10. ÀîºÍÍú£¬ºÎ÷ÏÈ, ÆÖÊÙÔÂ, ͯ²½¸ß£¬³Âå°Öé. ¼±ÐÔϱÚÐļ¡¹£ÈûÔ¤ºó·ÖÎö. ÁÙ´²ÐÄѪ¹Ü²¡ÔÓÖ¾ 1996, 12: 71-74.