öλÔÓéÀֵǼÈë¿ÚÏÂÔØ

µ¼Ê¦ÐÕÃû£ºÊæÏþºê
ÐÔ±ð£º
ÈËÆøÖ¸Êý£º117

ËùÊôԺУ£º´óÁ¬Ò½¿Æ´óѧ
ËùÊôԺϵ£ºÖÐÎ÷Ò½½áºÏÑо¿Ôº
Ö°³Æ£º¸±½ÌÊÚ
µ¼Ê¦ÀàÐÍ£º²©µ¼
ÕÐÉúöλÔÓéÀֵǼÈë¿ÚÏÂÔØ£º
Ñо¿ÁìÓò£º 1.ÌìȻҩÎï»îÐԳɷֵÄɸÑ¡£¬´ÓÌìȻҩÎïÖз¢ÏÖ»îÐԳɷֻòÏȵ¼»¯ºÏÎïÊÇÐÂÒ©Ñз¢µÄÖØҪ;¾¶Ö®Ò»£¬... [Õ¹¿ª]


Ñо¿ÁìÓò£º 1.ÌìȻҩÎï»îÐԳɷֵÄɸÑ¡£¬´ÓÌìȻҩÎïÖз¢ÏÖ»îÐԳɷֻòÏȵ¼»¯ºÏÎïÊÇÐÂÒ©Ñз¢µÄÖØҪ;¾¶Ö®Ò»£¬±¾Ñо¿½¨Á¢ÔÚÌìȻҩÎï·ÖÀëÖƱ¸»ù´¡ÉÏ£¬Õë¶ÔÖ×ÁöµÈÖØ´ó¼²²¡£¬½¨Á¢ÌåÍâ¡¢ÄÚʵÑéÄ£ÐͽøÐÐɸÑ¡£¬Ïà¹Ø»îÐԳɷֽøÒ»²½½øÐÐÁÙ´²Ç°ÆÀ¼Û£»2.¿¹Ö×ÁöÒ©ÎïµÄ·Ö×ÓÒ©Àíѧ¼°·Ö×ÓÉúÎïѧÑо¿£¬Ö×Áö×éÖ¯±ÈÕý³£×éÖ¯´úлÍúÊ¢£¬ÓÈÒÔ¶ñÐÔÖ×Áö¸üΪÃ÷ÏÔ£¬Í¨¹ýHPLC¡¢LC-MS/MSµÈ¼¼Êõ¶ÔÒ©ÎïÔÚÖ×Áöϸ°ûÖеĴúлÌصã½øÐзÖÎö£¬²¢¶ÔÆä½øÐзÖ×ÓÒ©ÀíѧÆÀ¹À£¬½ø¶øÔÚÐźÅͨ·¡¢×÷ÓðеãÉϽøÐзÖ×ÓÉúÎïѧ¼ì²â£¬ÒÔ̽ÇóÒ©ÎïµÄ¸öÐÔ»¯ÖÎÁƼ°ÉúÎï±ê¼ÇÎïɸѡ¡£ [ÊÕÆð]




¸öÈ˼òÊö :
ÊæÏþºê£¬²©Ê¿£¬¸±½ÌÊÚ£¬²©Ê¿Éúµ¼Ê¦¡£ÖйúÒ©Àíѧ»á»áÔ±£¬Öйúϸ°ûÉúÎïѧ»á»áÔ±£¬ÁÉÄþʡϸ°ûÉúÎïѧ»áÖÐÒ©»¯Ñ§·Ö»áÀíÊ¡£Ö÷Òª´ÓÊÂÌìȻҩÎÖ×Áö»îÐԳɷֵÄɸѡ¼°Æä·Ö×ÓÒ©ÀíѧºÍ·Ö×ÓÉúÎïѧÑо¿£¬Õë¶ÔÒ©ÎïÔÚÖ×Áöϸ°ûÄڵĴúлÀàÐÍ¡¢´úлø¼°Æä·Ö×Ӱеã½øÐÐ̽ÌÖ£¬È·Á¢Ò©ÎÖ×ÁöÓÐЧ»îÐÔÐÎʽ£¬²¢½¨Á¢¶¯ÎïÖ×ÁöÄ£ÐÍ£¬½øÐÐÒ©ÎïÁÙ´²Ç°É¸Ñ¡¼°Ö×Áö¸öÐÔ»¯ÖÎÁÆ¡£

¿ÆÑй¤×÷ :
ÔÚÑÐÏîÄ¿1. ¹ú¼Ò×ÔÈ»¿Æѧ»ù½ðÃæÉÏÏîÄ¿£¬¡°»ùÓÚÁ½ÖÖÔ­·¢ÐÔÄÔÖ×ÁöµÄ°×޼«´¼´úлÌص㼰ÆäÓ뿹°©»îÐÔ¹ØϵµÄÑо¿¡±£¬ÏîÄ¿¸ºÔðÈË¡£2.Öйú²©Ê¿ºó¿Æѧ»ù½ðÏîÄ¿£¬¡°°×޼«´¼ÔÚ½ºÖÊĸϸ°ûÁöÖдúлÐÎʽÑо¿¡±£¬ÏîÄ¿¸ºÔðÈË¡£3. ÁÉÄþÊ¡½ÌÓýÌü´´ÐÂÍŶÓÏîÄ¿£¬¡°°×޼«´¼¿¹Ëèĸϸ°ûÁö´úл²úÎï¼°Æä´úлøµÄ¼ø¶¨¡±£¬ÏîÄ¿¸ºÔðÈË¡£4.ÁÉÄþÊ¡½ÌÓýÌüÇàÄê»ù½ðÏîÄ¿£¬¡°éÎƤËØ¿¹Ð¡Êó°òë×°©·Ö×Ó»úÖÆÑо¿¡±£¬ÏîÄ¿¸ºÔðÈË¡£
´ú±íÐÔÎÄÕÂ1. Shu XH, Li H, Sun XX, Wang Q, Sun Z, Wu ML, Chen XY, Li C, Kong QY, Liu J. Metabolic patterns and biotransformation activities of resveratrol in human glioblastoma cells: relevance with therapeutic efficacies. PLoS One. 20116:e27484.
2. Shu XH, Li H, Sun Z, Wu ML, Ma JX, Wang JM, Wang Q, Sun Y, Fu YS, Chen XY, Kong QY, Liu J.Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells. Biochem Pharmacol. 201079:1516-1525.
3. Shu XH, Li H, Sun Z, Ma JX, Sun Y,Wu ML, Fu YS, Yang Y, Zhang KL, Wang Q, Kong QY,Chen XY, Liu J.Resveratrol in human medulloblastoma cells: Metabolism and induction of differentiation and apoptosis. J Biotechnol. 2008,136s:179-180.
4. Sun Z, Li H, Shu XH, Shi H, Chen XY, Kong QY, Wu ML, Liu J. Distinct sulfonation activities in resveratrol-sensitive and resveratrol-insensitive human glioblastoma cells. FEBS J. **:2381-2392.
5. Li CG, Li ML, Shu XH, Liu YJ, Wu WS. Antitumor effects of recombinant human interleukin-6 on mouse bladder carcinoma through Fas-mediated apoptosis. Cancer Chemother Pharmacol. 201066:981-986.