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½üÄê´ú±íÐÔSCIÂÛÎÄ£º1.Tingting Yang, Ting Shu, Guanlan Liu, Huifang Mei, Xiaoyu Zhu, Xin Huang, Luyong Zhang, Zhenzhou Jiang*. Quantitative profiling of 19 bile acids in rat plasma, liver, bile and different intestinal section contents to invstigate bile acid homeostasis and the application of temporal variation of endogenous bile acids.Journal of Steroid Biochemistry & Molecular Biology. 2017, 172:69-78.2.Guo Hongli, Hozeifa M. Hassan, Ding Pingping, Wang Shaojie, Chen Xi, Wang Tao, Sun Lixin,Zhang Luyong*,Jiang Zhenzhou*. Pyrazinamide-induced hepatotoxicity is alleviated by 4-PBA via inhibition of the PERK-eIF2¦Á-ATF4-CHOP pathway.Toxicology. 2017, 378:65-75.3.Hozeifa M. Hassan, Guo Hongli, Bashir A. Yousef, Ding Pingping, Zhang Luyong*, Jiang Zhenzhou*. Dexamethasone pretreatment alleviates isoniazid/lipopolysaccharide hepatotoxicity: inhibition of inflammatory and oxidative stress.Frontier in Pharmacology. 2017, 8(133):e1-e13.4.Yu Linxi, Liu Xiaoxin, Yuan Zihang, Li Xiaojiaoyang, Yang Hang, Yuan Ziqiao, Lixin Sun,Zhang Luyong*, Jiang Zhenzhou*. SRT1720 alleviates ANIT-induced cholestasis in a mouse model.Frontier in Pharmacology. 2017, 8(256):e1-e17.5.Li Xiaojiaoyang, Liu Runping, Luo Lan, Yu Linxi, Chen Xin, Sun Lixin, Wang Tao, Phillip B. Hylemon,Zhou Huiping*, Jiang Zhenzhou*, Zhang Luyong*. Role of AMP?activated protein kinase ¦Á1 in17¦Á-ethinylestradiol?induced cholestasis in rats.Archives of Toxicology.2017, 91:481-494.6.Hozeifa Mohamed Hassan, Guo Hongli, Bashir Alsiddig Yousef, Mounia Guerram, Aida Mejda Hamdi, Zhang Luyong*, Jiang Zhenzhou*. Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment. Antimicrobial Agents and Chemotherapy. 2016, 60(9):5285-5293.7.Guo Hongli, Hozeifa M. Hassan, Zhang Yun, Dong Sizhe, Ding Pingping, Wang Tao, Sun Lixin,Zhang Luyong*, Jiang Zhenzhou*.Pyrazinamide induced rat cholestatic liver injury through inhibition of FXR regulatory effect on bile acid synthesis and transport.Toxicological Sciences. 2016. 152(2):417-428.8.Li Xiaojiaoyang, Liu Runping, Yu Linxi, Yuan Zihang, Sun Rong, Yang Hang, Zhang Luyong,Jiang Zhenzhou*. Alpha-naphthylisothiocyanate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes.Toxicology. 2016, 37:106-115.9.Li Xiaojiaoyang, Yuan Zihang, Liu Runping, Hozeifa M. Hassan, Yang Hang, Sun Rong, Zhang Luyong*, Jiang Zhenzhou*. UDCA and CDCAalleviate17¦Á-ethinylestradiol-induced cholestasis through PKA-AMPK pathwaysin rats.Toxicology and Applied Pharmacology.2016, 311:12-25.10.Zhang Yun#, Guo Hongli#, Hozeifa M. Hassan, Ding Pingping, Wang Tao, Sun Lixin,Zhang Luyong*, Jiang Zhenzhou*. Pyrazinamide induced hepatic injury in rats through inhibiting the PPAR¦Á pathway.Journal of Applied Toxicology. 2016, 36(12):1579-1590 .11.Yu Linxi, Liu Xiaoxin, Li Xiaojiaoyang, Yuan Zihang, Yang Hang, Zhang Luyong*, Jiang Zhenzhou*.Protective effects of SRT1720 via theHNF1¦Á/FXRsignalling pathway and anti-inflammatory mechanisms in mice with estrogen-induced cholestatic liver injury.Toxicology Letters.2016, 264:1-11.