öλÔÓéÀֵǼÈë¿ÚÏÂÔØ

µ¼Ê¦ÐÕÃû£ºÂ½ÌÎ
ÐÔ±ð£ºÄÐ
ÈËÆøÖ¸Êý£º272

ËùÊôԺУ£ºÖйúÒ©¿Æ´óѧ
ËùÊôԺϵ£ºÀíѧԺ
Ö°³Æ£º½ÌÊÚ
µ¼Ê¦ÀàÐÍ£º²©µ¼
ÕÐÉúöλÔÓéÀֵǼÈë¿ÚÏÂÔØ£ºÒ©Îﻯѧ¡¢»¯Ñ§
Ñо¿ÁìÓò£º £¨Ò»£©ÐÂÒ©·Ö×ÓÉè¼ÆÓëºÏ³ÉÑо¿£»£¨¶þ£©¼ÆËã»ú¸¨ÖúÒ©ÎïÉè¼Æ£»£¨Èý£©ÓлúºÏ³É»¯Ñ§£»£¨ËÄ£©Ò©ÎïÉúÎï... [Õ¹¿ª]


Ñо¿ÁìÓò£º £¨Ò»£©ÐÂÒ©·Ö×ÓÉè¼ÆÓëºÏ³ÉÑо¿£»£¨¶þ£©¼ÆËã»ú¸¨ÖúÒ©ÎïÉè¼Æ£»£¨Èý£©ÓлúºÏ³É»¯Ñ§£»£¨ËÄ£©Ò©ÎïÉúÎïͳ¼ÆÓë¼ÆËãҩѧ¡£ [ÊÕÆð]




ͨѶ·½Ê½ :
°ì¹«µç»°£º**
µç×ÓÓʼþ£ºlutao@cpu.edu.cn
ͨѶµØÖ·£º½­ËÕÊ¡ÄϾ©ÊÐͯ¼ÒÏï24ºÅ£¬ÖйúÒ©¿Æ´óѧ£¨210009£©


¸öÈ˼òÊö :
½ÌΣºÄУ¬1963Äê4Ô³öÉú£¬½ÌÊÚ£¬Ò©ÎﻯѧöλÔÓéÀֵǼÈë¿ÚÏÂÔز©Ê¿Éúµ¼Ê¦£¬½­ËÕÊ¡½ÌѧÃûʦ£¬ÏÖÈÎÖйúÒ©¿Æ´óѧ¸±Ð£³¤¡£1984Äê7Ô±ÏÒµÓÚÔ­ÄϾ©Ò©Ñ§ÔºÒ©ÎﻯѧöλÔÓéÀֵǼÈë¿ÚÏÂÔØ»ñѧʿѧ룬1989Äê6Ô±ÏÒµÓÚÖйúÒ©¿Æ´óѧҩÎﻯѧöλÔÓéÀֵǼÈë¿ÚÏÂÔØ»ñ˶ʿѧ룬2001Äê5Ô±ÏÒµÓÚÖйúÒ©¿Æ´óѧҩÎﻯѧöλÔÓéÀֵǼÈë¿ÚÏÂÔØ»ñ²©Ê¿Ñ§Î»¡£2004Äê5Ô±»Æ¸Îª½ÌÊÚ¡£2006Äê11Ô±»Æ¸Îª²©Ê¿Éúµ¼Ê¦¡£2000Äê10ÔÂÈλù´¡²¿¸±Ö÷ÈΣ¬2003Äê2ÔÂÈλù´¡²¿Ö÷ÈΣ¬2012Äê7ÔÂÈÎÀíѧԺԺ³¤¡£2013Äê7ÔÂÈÎÖйúÒ©¿Æ´óѧ¸±Ð£³¤¡£ÏÖµ£Èιú¼Ò»ù½ðίÉúÃü¿Æѧ²¿Í¨Ñ¶ÆÀÒéר¼Ò£¬¹ú¼Ò·¢¸ÄίҩƷ¼Û¸ñÂÛÖ¤ÖÐÐÄÆÀÉóר¼Ò£»½ÌÓý²¿±¾¿Æ½ÌѧºÏ¸ñÆÀ¹Àר¼Ò£»½­ËÕ»¯Ñ§»¯¹¤Ñ§»áÀíÊ¡¢Óлú»¯Ñ§öλÔÓéÀֵǼÈë¿ÚÏÂÔØίԱ»áίԱµÈѧÊõÖ°Îñ¡£¡¶ÖйúÒ©¿Æ´óѧѧ±¨¡·±àί£¬¶à´ÎÊÜÑûΪEuropean of Medicinal Chemistry¡¢Journal of Molecular ModelingµÈ¶àÖÖSCIÆÚ¿¯µ£µ±Éó¸åÈË¡£

¿ÆÑй¤×÷ :
ÒÑÍê³É¹ú¼Ò¼°Ê¡²¿¼¶¿ÎÌâ¶àÏĿǰ¿ÎÌâ×éÔÚÑÐÏîÄ¿Ö÷ÒªÓйú¼Ò×ÔÈ»¿Æѧ»ù½ð12Ï½ÌÓý²¿Íâ¹úÎĽÌר¼Ò»ù½ðÒ»Ïî¡£×ÔÖ÷Ñз¢µÄCDK/Flt3¶à°ÐµãÒÖÖƼÁ×÷ΪÁÙ´²Ç°ºòÑ¡»¯ºÏÎïÒÔÎåǧÍòºÏͬ¼Û¸ñתÈøøÉϺ£¸´ÐÇÒ½Ò©²úÒµ·¢Õ¹ÓÐÏÞ¹«Ë¾¡£ÒÑÖ¸µ¼Ë¶Ê¿Ñо¿Éú34Ãû£¬Ö¸µ¼²©Ê¿Ñо¿Éú7Ãû¡£¿ÎÌâ×éÏÖÓÐÖ¸µ¼½Ìʦ12Ãû£¬²©Ê¿Éú9Ãû£¬Ë¶Ê¿Ñо¿Éú46Ãû¡£
½üÆÚ·¢±íÖ÷ÒªÂÛÖø£º
1. Du Ding*, Hu Zhongyuan, Jin Jianlin, Lu Yingyan, Tang Weifang, Wang Bo, Lu Tao*. N-Heterocyclic Carbene-Catalyzed Three-Component Domino Reaction of Alkynyl Aldehydes with Oxindoles. Organic Letters 2012, 14(5), 1274-1277 2. Qingfa Zhou*, Xueping Chu, Weifang Tang, Tao Lu*, An efficient one-pot synthesis of 1,4-disubstituted 3-amino-2-pyridone derivatives via three-component reactions of alkynyl aldehydes and amines with ethyl 2-((diphenylmethylene)amino)acetate. Tetrahedron 68 (2012) 4152-4158 3. Botao Xin, Weifang Tang, Yue Wang, Guowu Lin, Haichun Liu, Yu Jiao, Yong Zhu, Haoliang Yuan, Yadong Chen*, Tao Lu*, Design, synthesis and biological evalution of ¦Â-carboline derivatives as novel inhibitors targeting B-Raf kinase. Bioorganic & Medicinal Chemistry Letters 22 (2012) 4783¨C47864. Wenhai Li*, Yue Wang, Tao Lu*, Facile synthesis of 1-aminoisoquinolines via the tandem reactions of 2-alkynylbenzaldoximes with isothiocyanates. Tetrahedron 68 (2012) 6843-68485. Yingyan Lu, Weifang Tang, Yu Zhang, Ding Du* and Tao Lu*, N-Heterocyclic Carbene-Catalyzed Annulations of Enals and Ynals with Indolin-3-ones: Synthesis of 3,4-Dihydropyrano[3,2-b]indol-2-ones. Adv. Synth. Catal. 2013, 355, 321 ¨C 3266. Chen Wang, De-Kai Ye, Yun-Yi Wang, Tao Lu* and Xing-Hua Xia*, Insights into the ¡®¡®free state¡¯¡¯ enzyme reaction kinetics in nanoconfinement. Lab on a Chip 2013, 13, 1546¨C15537. Qing-Fa Zhou*, Xue-Ping Chu, Fei-Fei Ge, Cheng Li, Tao Lu*, Stereoselective syntheses of functionalized spirocyclopenteneoxindoles via triphenylphosphine-catalyzed [3+2] cycloaddition reactions. Mol. Divers. 2013, 17:563¨C571