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´ú±íÐÔÂÛÎÄ:1. Yang Lu, Jason R. Slizgi, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock, Kim L.R. Brouwer. Hepatocellular disposition and transporter interaction of tolvaptan and metabolites in human sandwich-cultured hepatocytes. Drug Metabolism and Disposition. 2016 (in press)2. Jason R. Slizgi, Yang Lu (equal contribution), Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock, Kim L.R. Brouwer. Inhibition of human hepatic bile acid transporters by tolvaptan and metabolites: A contributing factor to drug-induced liver injury. Toxicological Sciences. 2016,149: 237-250.3. Yang Lu, Takeo Nakanishi, Hosomi Atsushi, Hisakazu Komori, Ikumi Tamai. In-vitro evidence of enhanced BCRP-mediated intestinal urate secretion by uremic toxins in Caco-2 cells. Journal of Pharmacy and Pharmacology. 2015, 67:170-177.4. Yang Lu, Takeo Nakanishi, Miki Fukazawa, Ikumi Tamai. How does whisky lower serum urate level? Phytotherapy Research. 2014, 28: 788-790.5. Yang Lu, Jing Jing, Weichao Ren, Jing Zhu, Zhixia Qiu, Ning Li, Xiaonan Li, Di Zhao, Harendra S. Parekh, Xijing Chen. Biliary excretion of glycyrrhetinic acid: glucuronide-conjugate determination following a pharmacokinetic study of rat bile. Phytotherapy Research. 2014, 28: 1887-1889.6.Yang Lu, Takeo Nakanishi, Ikumi Tamai. Functional cooperation of SMCTs and URAT1 for renal reabsorption transport of urate. Drug Metabolism and Pharmacokinetics. 2013, 28 (2): 153-158.7. Fang Fang, Yang Lu, Yue Liang, Jing Zhu, Jiake He, Jianheng Zheng, Ning Li, Yue Tang, Jiabi Zhu, Xijing Chen. Evaluation of insulin lispro and biosynthetic human insulin in pulmonary absorption: in vivo and in vitro studies. Pharmazie. 2012, 67: 706-711.8. Bing Yang, Yang Lu (equal contribution), Jianheng Zheng, Jing Zhu, Jiake He, Di Zhao, Pengfei Song, Xijing Chen. Pharmacokinetics of the prodrug thiamphenicol glycinate and its active parent compound thiamphenicol in beagle dogs following intravenous administration. Xenobiotica. 2011, 41: 226-231.9. Weichao Ren, Yang Lu, Jing Jing, Jing Zhu, Di Wan, Di Zhao, Jianheng Zheng, Fang Fang, Yan He, Xijing Chen. Determination of glycyrrhizin in dog plasma by liquid chromatography-mass spectrometry and its application in pharmacokinetic studies. European Journal of Mass Spectrometry. 2010, 16: 673-678.10. Yang Lu, Jing Zhu, Xijing Chen, Ning Li, Feifei Fu, Jiake He, Guangji Wang, Lingli Zhang, Yi Zheng, Zhixia Qiu, Xue Yu, Deen Han, Lei Wu. Identification of human UDP-glucuronosyltransferase isoforms responsible for the glucuronidation of glycyrrhetinic acid. Drug Metabolism and Pharmacokinetics. 2009, 24: 523-528.

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