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Zhou T, Xu W.D., Xu C.L., Gao X, Hou J.G., Ren S.C., Yang B, Wei G.L., Sun Y., Chen CY, Guo C.X., Tong Y., Karl Zhou, Sun Y.H. A first-in-human phase 1 study of proxalutamide (GT0918), a dual MOA androgen receptor blocker in patients with advanced CRPC. 2017.35.15_suppl.e16511 Journal of Clinical Oncology
Tong, Y., Chen CY., Wu J., Zhang HH.,(2013) Discovery of potent androgen receptor antagonists for treating CRPC and AR-Positive breast cancer£¬Cancer Research Volume 73, Issue 8, Supplement 1 ,2460.
Tong, Y., Chen CY., Wu J., Zhang HH.,(2014) Preclinical Studies and Clinical Plan for Proxalutamide (GT0918), A Potent Androgen Receptor Pathway Inhibitor, Cancer Research Volume 74, Issue 19,614
Tong, Y., Song, W., and Crystal, R.G. (2001) Combined intratumoral injection of bone marrow-derived dendritic cells and systemic chemotherapy to treat pre-existing murine tumors. Cancer Research 61(20):7530-7535.
Song, W., Tong, Y., Carpenter, H., Kong, H.L., Rafii, S., Granstein, R., Moore, M.A.S., and Crystal, R.G. (2000). Induction of persistent, antigen-specific, therapeutic antitumor immunity by dendritic cells genetically modified with an adenoviral vector to express a model tumor antigen. Human Gene Therapy, 7(24):2080-2086.
Banerjee, D., Tong, Y., Liu-Chen, X., Capiaux, G., Ercikan-Abali, E.A., Takebe, N., O'Conner, O.A., and Bertino, J.R. (1999). Protection of bone marrow cells from toxicity of chemotherapeutic agents targeted toward thymidylate synthase by transfer of mutant forms of human thymidylate synthase cDNA. Prog. Exp. Tumor Res. 36:107-114.
Sapse, D.S., Tong, Y., Bertino, J.R., and Sapse, A.M. (1999) Ab initio studies of some amino acid residue complexes with 4-mercaptopyridine as a model for Thymitaq (AG337), an inhibitor of thymidylate synthase. Cancer Invest. 17(6):396-401.
Tong, Y., Liu-Chen, X., Ercikan-Abali, E.A., Zhao, S.C., Banerjee, D., Maley, F., and Bertino, J.R. (1998) Probing the folate binding site of human thymidylate synthase by site-directed mutagenesis. Generation of mutants that confer resistance to raltitrexed, Thymitaq and BW1843U89. J. Biol. Chem., 273:31209-31214.
Tong, Y., Liu-Chen, X., Ercikan-Abali, E.A., Banerjee, D., and Bertino, J.R. (1998) Isolation and characterization of Thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistance mutants of human thymidylate synthase from ethlmethanesulfonate-exposed human sarcoma HT1080 cells. J. Biol. Chem., 273:11611-11618.
Ercikan-Abali, E.A., Mineishi, S., Tong, Y., Waltham, M.C., Banerjee, D., Nakahara, S., Sadelain, M., and Bertino, J.R. (1996). Active site directed double mutants of dihydrofolate reductase. Cancer Research 56:4142-4145.
Chou, T.C., Motzer, R.J., Tong, Y., and Bosl, G.J. (1994). Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplain against human teratocarcinoma cell growth: a rational approach to clinical protocol design. J. Natl. Cancer Intl. 86:1517-1709.
Banerjee, D., Zhao, S.C., Tong, Y., Steinherz, J., Gritsman, K., and Bertino, J.R. (1994). Transfection of a nonactive site mutant murine DHFR cDNA (the tryptophan 15 mutant) into Chinese hamster ovary and mouse marrow progenitor cells imparts MTX resistance in vitro. Cancer Gene Therapy 1:181-184.
Tong, Y., Jin, X.L., Liu, Y.Q., Xu, X.J., and Tang, Y.Q. (1991). Synthesis and crystal structure of the azido dinuclear copper(II) cryptate of macrocyclic ligands [Cu2(N3)2(C16H38N6)](ClO4)2. Acta Chimica Sinica(Ch.) 49:48-52.
Jin, X.L., Tong, Y., Xu, X.J., and Tang, Y.Q. (1991). Synthesis and crystal structure of the binucleating macrocyclic monohydroxo-bridged dicopper(II) complex [Cu2(OH)(ClO4)(C16H38N6)](ClO4)2CHCl3. J. Inorg. Chem.(Ch.) 7:69-75.
Jin, X.L., Tong, Y., Xu, X.J., and Tang, Y.Q. (1991). The synthesis and crystal structure of the thiocuanato dinuclear copper(II) complex of macrocyclic ligand [Cu2(SCN)3(C16H38N6)]2(ClO4)2. Acta Physico-Chimica Sinica(Ch.) 7:323-328.
Jin, X.L., Jiang, Y.J., and Tong, Y. (1989). Synthesis and crystal structure of (diethylenetriamine)(acetate) zinc perchlorate. J. Struct. Chem.(Ch.) 8:229-231.
Tong, Y., Jin, X.L., Xu, X.J., and Tang, Y.Q. (1988). The superoxide dismutase and its model chemistry (Review). Journal of Biochemical Pharmaceutical(Ch.) 44(2):23-28.
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