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Dr. Bo LEI (Àײ¨)

Professor, Group Leader (½ÌÊÚ¡¢Ñо¿Ð¡×éÖ÷ÈΣ©

Nanoscale Hybrid Biomaterials and Tissue Regeneration group(ÄÉÃ׸´ºÏÉúÎï²ÄÁÏÓë×éÖ¯ÔÙÉúÑо¿Ð¡×飩

Group website: http://gr.xjtu.edu.cn/web/rayboo

Contacts: rayboo@xjtu.edu.cn, 029-83395361

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Research Interests(Ñо¿·½Ïò)£º

£¨1£©Fabrication and properties of novel nanoscale bioactive biomaterialsÐÂÐÍÄÉÃ×ÉúÎï»îÐÔÒ½ÓòÄÁϵĺϳÉÓëÐÔÄÜÑо¿£¨ÄÉÃ×¾§/ÄÉÃ×Á£/ÄÉÃ׶à¿×Ö§¼Ü£©¡£

£¨2£©Synthesis and properties of Biodegradable polymer nanohybrids (nanocomposites)¿ÉÎüÊո߷Ö×ÓÄÉÃ׸´ºÏÒ½ÓòÄÁϺϳÉÓëÐÔÄÜÑо¿£¨ÄÉÃ×Á£/±¡Ä¤/Ë®Äý½º/¶à¿×Ö§¼Ü£©¡£

£¨3£©Bio-functionalization of nano-biomaterials and polymer hybridsÄÉÃ×ÉúÎï²ÄÁÏÓë¸ß·Ö×Ó¸´ºÏ²ÄÁÏÉúÎ﹦ÄÜ»¯Ñо¿£¨Ó«¹â/µç»îÐÔ/´ÅÐÔ/¿¹¾ú/ϸ°û½éµ¼£©

£¨4£©Biomedical applications of nanoscale biomaterials and polymer nanohybridsÄÉÃ×ÉúÎï²ÄÁÏÓë¸ß·Ö×Ó¸´ºÏ²ÄÁÏÉúÎïҽѧӦÓÃÑо¿£¨×éÖ¯ÔÙÉúÓ빤³Ì¡¢»ùÒòϸ°ûÒ©ÎïÔØÌ塢ϸ°ûÓ°Ïñ¡¢°©Ö¢Õï¶ÏÖÎÁÆ£©

Research ID: http://www.researcherid.com/rid/B-9463-2009

Research Interests (Ñо¿ÄÚÈÝ)£º

¡ñ Biomimetic, biodegradable and bioactive polymer-silicate based hybrid biomaterials for bone tissue

regeneration and tissue engineering applications

¡ñ Biomimetic and bioabsorbable polymer-based hybrid biomaterials for skin and vascular tissue

regeneration and tissue engineering applications

¡ñ Smart and biomimetic drug/protein delivery system design and biomedical applications

¡ñ Biocompatibility (blood, tissue, cells) studies and evaluation for biomimetic hybrid biomaterials.

Representative Publications (´ú±íÐÔÂÛÎÄ)£º

1. Lei B, Chen X, Han X. Versatile fabrication of nanoscale sol-gel bioactive glass particles for highly efficient tissue regeneration. J. Mater. Chem, 2012, 22(33), 16906-16913 (IF=5.96). Link: http://pubs.rsc.org/en/content/articlepdf/2012/jm/c2jm31384g

2.Nanofibrous gelatin-silica hybrids scaffolds mimicking the native extracellular matrix (ECM) using thermally induced phase separation. J.Mater. Chem, 2012, 22(28), 14133-14140 (IF=5.96). Link: http://pubs.rsc.org/en/content/articlepdf/2012/jm/c2jm31290e

3. Lei B, Chen X, Han X, Li Z. Unique physical-chemical, apatite-forming properties and human marrow mesenchymal stem cells (HMSCs) response of sol-gel bioactive glass microspheres. J. Mater. Chem, 2011, 21 (34)12725-12734 (IF=5.96). Link: http://pubs.rsc.org/en/content/articlehtml/2011/jm/c1jm11547b

4. Lei B, Shin K H, Koh Y H, Kim H E. Bioactive glass microspheres as reinforcement for improving the mechanical properties and biological performance of poly(¦Å-caprolactone) polymer for bone tissue

regeneration. J. Biomed. Mater. Res. Part B, 2012, 100(4):967-975 (IF=2.22).

Link: http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.32659/full

5. Lei B, Shin K H, Moon Y W, Noh D Y, Koh Y H, Jin Y H, Kim H E. Synthesis and bioactivity of sol-gel derived porous, bioactive glass microspheres using chitosan as novel biomolecular template. Journal of American Ceramic Society, 2012; 95(1):30-33 (IF=2.27). Link: http://onlinelibrary.wiley.com/doi/10.1111/j.1551-2916.2011.04918.x/full

6. Lei B, Chen X, Wang Y, Zhao N, Du C, Fang L. Surface nanoscale patterning of bioactive glass to support cellular growth and differentiation. J. Biomed. Mater. Res. Part A, 2010, 9 (4),1091-1099 (IF=3.04). Link: http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.32776/full

7. Lei B, Chen X, Wang Y, Zhao N. Synthesis and in vitro bioactivity of novel mesoporous hollow bioactive glass microspheres. Materials Letters, 2009, 63(20)1719 (IF=2.30). Link: http://dx.doi.org/10.1016/j.matlet.2009.04.041

8. Lei B, Chen X, Wang Y, Zhao N, Miao G. Fabrication of porous bioactive glass particles by one step sintering. Materials Letters, 2010, 64(21): 2293-2295 (IF=2.30) Link: http://dx.doi.org/10.1016/j.matlet.2010.07.066

9. Lei B, Chen X, Wang Y, Zhao N, Du C, Fang L. Influence of sintering temperature on the pore structure and apatite formation of a sol-gel derived bioactive glass. Journal of the American Ceramic Society, 2010.93 (1) 32-35 (IF=2.27). Link: http://onlinelibrary.wiley.com/doi/10.1111/j.1551-2916.2009.03358.x/full