öλÔÓéÀֵǼÈë¿ÚÏÂÔØ

µ¼Ê¦ÐÕÃû£ººú¹ã¶«
ÐÔ±ð£ºÄÐ
ÈËÆøÖ¸Êý£º1108

ËùÊôԺУ£ºÊ¯ºÓ×Ó´óѧ
ËùÊôԺϵ£º¶¯Îï¿Æ¼¼Ñ§Ôº
Ö°³Æ£º¸±½ÌÊÚ
µ¼Ê¦ÀàÐÍ£º
ÕÐÉúöλÔÓéÀֵǼÈë¿ÚÏÂÔØ£ºÊÞҽѧ¡¢ÊÞÒ½
Ñо¿ÁìÓò£º ÊÞҽѧ¡¢
Ñо¿ÁìÓò£º ÊÞҽѧ¡¢ [ÊÕÆð]




ͨѶ·½Ê½ :
°ì¹«µç»°£º**
µç×ÓÓʼþ£ºhuguangdong1017@163.com
ͨѶµØÖ·£ºÐ½®Ê¯ºÓ×ÓÊÐʯºÓ×Ó´óѧ±±Ð£ÇøũѧԺÖ÷Â¥Î÷206


¸öÈ˼òÊö :
ºú¹ã¶«£¬Öй²²úµ³Ô±£¬Ë¶Ê¿Éúµ¼Ê¦£¬2014Äê6Ô²©Ê¿±ÏÒµÓÚÎ÷±±Å©ÁֿƼ¼´óѧÁÙ´²ÊÞҽѧöλÔÓéÀֵǼÈë¿ÚÏÂÔØ£¬²©Ê¿ÆÚ¼äʦ´ÓÈ«¹úÖøÃû¶¯ÎïÅßÌ¥¹¤³Ìר¼Ò¡¢Öйú¿Ë¡ÑòÖ®¸¸ÕÅÓ¿½ÌÊÚ£¬ÔÚÅ©Òµ²¿¶¯ÎïÉúÎï¼¼ÊõÖصãʵÑéÊÒÍê³ÉÏàÓ¦¿ÆÑÐÈÎÎñ£¬Ö÷Òª²ÎÓ롰ת»ùÒòÖØ´óרÏ¡¢¡°863¡±µÈÖØ´ó¿ÆÑÐÏîÄ¿¡£2014Äê9Ô½øÈëʯºÓ×Ó´óѧ¹¤×÷£¬Ö÷ÒªÑо¿·½ÏòΪ¼ÒÐó·±Ö³Ñ§¡¢¶¯ÎïÉúÎï¼¼ÊõÒÔ¼°¶¯ÎïÅßÌ¥¹¤³Ì¡£Ä¿Ç°Ö÷³ÖÊ¡²¿¼¶¿ÎÌâ1ÏУ£¨Ìü£©¼¶ÏîÄ¿2Ï·¢±íÂÛÎÄ14ƪ£¬»ñµÃ·¢Ã÷רÀû1ÏÖ÷±à½Ì²Ä2²¿¡£
»ñµÃʯºÓ×Ó´óѧÇàÄê½Ìʦ½Ìѧ¾ºÈüÓÅÐã½±1 Ï»ñµÃ´óѧÉú´´Ð´´ÒµÏîÄ¿ÓÅÐãÖ¸µ¼½Ìʦ½±1 Ïî¡£


¿ÆÑй¤×÷ :
1. ±øÍÅÈËÉç¾ÖÖصãÈ˲ÅÖ§³ÖÏîÄ¿¡£

2. ʯºÓ×Ó´óѧ¸ß²ã´ÎÈ˲ÅÏîÄ¿¡ªºÍÌïÑòFGF5»ùÒòCDsÇø¿Ë¡¡¢ÌØÕ÷·ÖÎö¼°RNA¸ÉÈÅƬ¶Îɸѡ

3. ʯºÓ×Ó´óѧÇàÄêÓ¦Óûù´¡Ñо¿ÏîÄ¿¡ªpiggyBacת×ù×ӽ鵼µÄ¸ßЧÃàÑòÌåϸ°û»ùÒòתÒÆϵͳ¹¹½¨
Ö÷ÒªÑо¿ÖصãÓÐÁ½¸ö£ºµÚÒ»ÊÇ»ù´¡Ñо¿·½Ã棬ͨ¹ý¶ÔmiRNAs¡¢lncRNAµÈС·Ö×Ó¹¦ÄÜɸѡºÍÑо¿£¬Ì½Ë÷ÆäÔÚ·´Û»¶¯Îï·±Ö³ÃâÒßÏà¹Øµ÷¿Ø»úÖÆÑо¿µÄÖØÒª×÷ÓᣵڶþÊÇÓ¦ÓÃÑо¿·½Ã棬½áºÏ·Ö×ÓÉúÎïѧ¼¼ÊõºÍ¶¯ÎïÅßÌ¥¹¤³ÌÏà¹Ø¼¼Êõ£¬Ì½Ë÷¸Ä½ø³£¼û¼ÒÐóºÍ¼ÒÇݸßЧ·±Ö³³ÌÐò£¬½«À´ÔÚʵ¼ùÖнøÐÐÍƹãºÍÓ¦Óá£
£¨1£©ºú¹ã¶«£¬ÂíÑ«. н®ÄÌÅ£ÎìÐ͸ÎÑײ¡¶¾RNA ¼ì²â¼°ÐòÁзÖÎö. ²¡¶¾Ñ§±¨£¬2010, 26 (1):27~32.

£¨2£©ºú¹ã¶«, ÌÆ˼¾²,ÂíÑ«. ÎìÐ͸ÎÑ×ÒßÃçÑо¿½øÕ¹. ÖйúÐóÄÁÊÞÒ½£¬2009, 36 (11)£º154~157.

£¨3£©ºú¹ã¶«£¬ÀîÉлª£¬ÂíÑ«£¬Íõ¾². н®²¿·ÖµØÇøÖí¸½ºìϸ°ûÌåºÍÔ²»·²¡¶¾»ìºÏ¸ÐȾµÄÕï¶Ï. ʯºÓ×Ó´óѧѧ±¨ (×ÔÈ»¿Æѧ°æ)£¬2009, 27 (6)£º712~714.

£¨4£©ºú¹ã¶«£¬²ÜÎıø£¬Ñî±ù£¬·ü࣬ º«Ïþ¸Õ£¬ ÔøÖ¾ÓÂ. ¹þÃÜÊÐÇÝÁ÷¸ÐÒßÇé¼à²â·ÖÎö.Öйú¶¯Îï¼ìÒߣ¬2005,22 (9)£º34-35.

£¨5£©ºú¹ã¶«£¬ ¸ßÔªÅô£¬Íõ¾²£¬Ö£ÀöÃ÷£¬ ÕÅÓ¿. N¶ËÈÚºÏTAT´©Ä¤ëĵÄpiggyBacת×ùøµÄÔ­ºË±í´ï¼°ÆäÔÚHEK 293ϸ°ûÖеŦÄÜÑéÖ¤. Å©ÒµÉúÎï¼¼Êõѧ±¨£¬2014£¬22(4): 406~414.

£¨6£©Guangdong Hu, Jing Wang, Hui Huang, Fusheng Quan, Jian Kang, Yongyan Wu, Yuanpeng Gao, Feng Su,Minghao Shao, and Yong Zhang. A Modified piggyBac Transposon System Mediated by Exogenous mRNA to Perform Gene Delivery in Bovine Mammary Epithelial Cells. Biotechnology and Bioprocess Engineering. 2014, 19: 1~13.

£¨7£©Jianmin Su, Guangdong Hu (¹²Í¬µÚÒ»), Yongsheng Wang, Dong Liang, Mingqing Gao, Hongzheng Sun, and Yong Zhang.Recombinant Human Growth Differentiation Factor 9 Improves Oocyte Reprogramming Competence and Subsequent Development of Bovine Cloned Embryos. Cellular Reprogramming (Completed Accepted) .

£¨8£©Jing Wang, Guangdong Hu , Zhi Lin, Lei He, Lei Xu, Yan-Ming Zhang*. Characteristic and functional analysis of a newly established porcine small intestinal epithelial cell line. PLOS ONE. (Major revision under review).

£¨9£©Jing Wang, Guangdong Hu, Wanjun Gao, Lei Xu, Pengbo Ning, Yanming Zhang* .Immortalized porcine intestinal epithelial cell cultures susceptible to porcine rotavirus infection. Journal of Virological Methods, 2014, 202, 87-94.

£¨10£©Xu Liu,Yongsheng Wang, Yuchen Tian, Yuan Yu, Mingqing Gao, Guangdong Hu, Feng Su, Shaohui Pan, Yan Luo, Zekun Guo, Fusheng Quan and Yong Zhang. Generation of mastitis resistance in cows by targeting human lysozyme gene to ¦Â-casein locus using zinc-finger nucleases. Proc. R. Soc. B,2014,281:1-10..

£¨11£©Yan Luo, Jun Liu, Yongsheng Wang, Jianmin Su, Yongyan Wu, Guangdong Hu, Mingqing Gao, Fusheng Quan,Yong Zhang. PhiC31 integrase-mediated genomic integration and stable gene expression in the mouse mammary gland after gene electrotransfer. J Gene Med 2013,15: 356¨C365..

£¨12£©Yan Luo, Jun Liu, Qingqing Liu, Liming Zheng, Yongsheng Wang, Jianmin Su, Guangdong Hu, Yong Zhang. Chicken hypersensitive site-4 insulator increases human serum albumin expression in bovine mammary epithelial cells modified with phiC31 integrase. Biotechnology letters, 35(4): 529-537..

£¨13£©Feng Su, Xin Liu, Guanghui Liu, Yuan Yu, Yongsheng Wang, Yaping Jin, Guangdong Hu, Song Hua, Yong Zhang. Establishment and Evaluation of a Stable Cattle Type II Alveolar Epithelial Cell Line. PLoS One 8: e76036..

£¨14£©»Æ»Ý£¬ºú¹ã¶«£¬¿µ½¡£¬ÇäËØÖ飬ÕÅÓ¿. PiggyBac (PB) ת×ù×ӽ鵼µÄÈ˶ËÁ£Äæת¼ø(hTERT) ϸ°ûÓÀÉú»¯ÔØÌåµÄ¹¹½¨¼°ÆäÑéÖ¤. ÉúÎ﹤³Ìѧ±¨£¬2014,30£¨8£©£º1182-1192¡£


½ÌÓý±³¾° :
2006Äê±ÏÒµÓÚʯºÓ×Ó´óѧ¶¯ÎïҽѧöλÔÓéÀֵǼÈë¿ÚÏÂÔØ£¬»ñµÃũѧѧʿѧλ£»2009Äê±ÏÒµÓÚʯºÓ×Ó´óѧԤ·ÀÊÞҽѧ˶ʿÑо¿ÉúöλÔÓéÀֵǼÈë¿ÚÏÂÔØ£¬»ñµÃũѧ˶ʿѧλ2014Äê6Ô²©Ê¿±ÏÒµÓÚÎ÷±±Å©ÁֿƼ¼´óѧÁÙ´²ÊÞҽѧöλÔÓéÀֵǼÈë¿ÚÏÂÔØ£¬»ñµÃũѧ²©Ê¿Ñ§Î»¡£